Today’s young people face enormous challenges, but as part to the new global economy and the explosion of information technology, they also have unparalleled opportunities to learn new skills and shape their own futures. With the founding of the International Youth Foundation (IYF) it was identified that building partnerships, both global and local would be critical to improve the lives and prospects of young people. This publication looks at the growth in inter-sectoral partnering in recent years, and explores a number of case studies involving IYF and its global partner network, as well as valuable lessons learnt. Increasing the effectiveness, scale and sustainability of proven approaches to meeting young people’s needs are key goals at the heart of IYF’s efforts. The report examines and aids efforts to develop mutually beneficial partnerships aimed at addressing a host of urgent development challenges.